Gene editing

Gene-editing, and targeting capabilities of components of gene-editing systems, can be harnessed to provide wide-ranging, practical applications, yet freedom to operate issues often pose ongoing challenges for pioneers and start-ups in this fast-moving, powerful field.  

Whilst there is immense focus on CRISPR gene-editing, older techniques continue to have applications, with the early systems providing impetus for further developments in genetic modification in the CRISPR field and beyond.  

HGF has one of the most experienced, commercially- minded teams in Europe focussed on gene-editing, with significant experience of involvement in European oppositions affecting the foundational CRISPR IP,  as well as advising on and patenting earlier gene-editing systems, such as TALENs.  

The core team of specialists that make-up the HGF CRISPR team are backed by a larger group of over 75 patent attorneys and solicitors, with backgrounds in life sciences, pharmaceuticals, chemistry and plant sciences.  

Specialising in gene-editing in the context of new human and animal therapies, viral diagnostics, developments in animal farming and microbiome, as well as plant protection and breeding, the HGF CRISPR team includes specialists from the firm’s AgBio team. This enables HGF to develop multidisciplinary IP strategies across this important and complex field.  

HGF works with pioneers of CRISPR technology, as well as for clients advancing the field of gene modification and applications of CRISPR, to those that endeavour to resolve important problems, such as antibiotic resistance and infection diagnostics. This wealth of expertise sees HGF attorneys conducting talks at international events and providing articles on IP developments in the fast-evolving CRISPR field, along with the broader genetic engineering sector.

Latest updates

Where Does the Real IP Value Lie in AI-Enabled Life Sciences?

After attending the BioTechX conference in Basel last week, talking to people working across pharma, biotech, AI, software, laboratory automation and data management, my main takeaway was clear: the conversation …

Read article

When AI Designs the Ingredient: Who Controls the Data, the Model and the Discovery?

AI-enabled discovery has drawn significant attention in pharmaceutical R&D, but its impact is extending into other industries, across ingredients, food, flavour, fragrance and industrial biotechnology. As AI models advance, the …

Read article

Protecting the AI Drug Discovery Ecosystem: Building an IP Stack Around Targets, Molecules and Medicines

Despite the considerable costs and effort in target identification, candidate generation, selection and advancement to clinical trials, 90% of candidates that enter clinical trials during drug discovery fail (Sun D, …

Read article

Agritech Thymes: UK-EU SPS agreement – what does it mean for plant breeders?

Since Brexit, the UK agrifood sector has faced difficulties, largely due to the requirement for additional certifications and controls, such as phytosanitary certificates and border checks. This has had a …

Read article

How Low Can You Go? T 0137/24, Percentage Sequence Identity Claims and Divergent EPO and USPTO Approaches

Key takeaways Increasing percentage sequence identity thresholds may be selected from a disclosed convergent list without adding matter, provided the amendment does not create a new technical combination; Broader percentage …

Read article
Event - 18th November 2026

HGF Venture: Funding the Future

Join fellow life sciences founders, investors and business leaders for an evening of drinks and networking in Cambridge on the 18th November, 5-9pm. Featuring an investor-founder round table and an …

Event details

Designing the Exit: IP Strategy for Venture-Backed Biotech

In venture-built biotech, value is not created at the point of exit, but is designed into the asset from the very beginning. The earliest decisions made around a scientific discovery …

Read article

Five Questions VCs Should Ask About IP Before They Invest

Intellectual property diligence too often starts with the wrong question: how many patents does the company have? For venture investors, that is rarely the most revealing answer. The real issue …

Read article

Let's talk

If you would like to discuss how HGF could help you, contact one of our gene editing technologies specialists.